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KMID : 0613820110210060858
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Journal of Life Science
2011 Volume.21 No. 6 p.858 ~ p.864
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Functional Properties of Walnut in Cosmetics
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Kim Mi-kyung
Kim Jin-Sung
Jo Bun-sung
Kim Jung-Hwan
Lee In-cheol
Lee Myung-sup
Cho Young-Je
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Abstract
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The phenolic compounds of walnut extracts by various solvents were shown to be 24.3 ㎎/g in hot water, 34.4 ㎎/g in ethanol, 32.5 ㎎/g in methanol and 15.1 ㎎/g in acetone. In a comparison of phenolic compounds from hot water and different concentrations of ethanol, which are harmless, 60% ethanol extract and hot water extract were 34.7 ㎎/g, 24.6 ㎎/g. The electron donating ability (EDA) of walnut extracts in hot water and 60% ethanol were 78.1% and 80.6%. According to ABTS radical cation decolorization for antioxidant activity, hot water and 60% ethanol extract showed high antioxidant activities of 98.1% and 98.3%. Antioxidant protection factor (PF) were 1.1±0.2 PF and 1.1±0.4 PF in hot water and 60% ethanol extract. In TBARs inhibitory activity, each extract showed high antioxidant activities at 60% and 75%. Anti-inflammation effects of walnut extract were tested, and inhibition of NO was 50% in 100 ㎍/㎖ phenolics. Inhibitory activity against iNOS and COX-2 were shown, through Western blot, to be 10% in 100 ㎍/㎖ phenolics. Tyrosine inhibitory activity of 60% ethanol extract was 43%, and astringent effect of 60% ethanol extract was 55%. These results suggest that walnut extracts are suitable for functional cosmetics requiring skin-whitening and anti-wrinkle activity.
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KEYWORD
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Walnut, functional activities, cosmetic, antioxidant, tyrosinase activity, anti-inflammation effect, astringent activity
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